SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de617549996034b1a2cd3334f0e4ca9259a85c29d4ebc76f65a5865676ce146' 
  AND token = 'LqSD0dE+uPGGXQC8VMUDDVIqwdTxuiLwLWZZOcub5WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}