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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6cfe84eaac750a37c498ae53af09ed9da80d830875faab82df7e6ec6972eba' 
  AND token = 'jS3A1I6Nd2IUfx2/cyOsQH++qEETYfqLLn+XxOV+nRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}