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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c82d6dfe43e4d78e30dcad276721c4ec7ec5efc206efd4dcda303289cd9d9ba' 
  AND token = 'JvMBaJLJWr+zgbvdVgH3wc0KddbpjeV6fh8vyJ9tgnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}