SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4df9c0f96ccce4b437b736ba299c61931069b48b1cbb7bba22150e87acbabb' 
  AND token = 's6fYf2MLja3meSiVElPvaTEzx1/d/dydLw68anTQeAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}