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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d0a3d47899ce1a914fbf300513e35b359e4a3bcc2552bfb2d2bc88b6e4a291' 
  AND token = '4yFxdIziP/SW1fFTJibrNInhDs1mHL5Rl2tyUwt9ngk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}