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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa88bbe80413467090748eb8d4c6f8bf41007752b4a49d0d0f14287a3de94b34' 
  AND token = 'quIPGk5O2mrg6ZTLrPe4D3qGeKmweAlvcFsVALMojxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}