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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd28ee1a5a1ca998ee0dab787dce3d6bee66233a4abf00f533acc7a777bcb2650' 
  AND token = 'JFHgerei4eA+1cNDZ453knagk+AfERvqkWKcQ7dF22c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}