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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81280f38613a08edda7b94a1b1761e8c98c4c03d369af4f300c6c85a0a5de231' 
  AND token = 'Zod319acrcAICVyi4rvx2o7TJfaeHfffQM5CxZ57poE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}