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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105bce080c745f8609f2e34eb1608bc87fbcbbfd4841ee9b96c35195d2af5e0d' 
  AND token = 'I4upIE++18lfW2a+Q/142aVpEGGNPAbWRKbiYWm7N80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}