SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc185515054b4e197dcc1e961a67db77ae9f375f59cc4aecb4913c0b3698b573' 
  AND token = 'YuDg/R5UvE7Uo5cKID0S+5luRMDNqIi4hMrfkLHbGJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}