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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab161dbd271872f3164c09280bb549bff81d1696b7609cc5d539f181fc9a29e' 
  AND token = 'mPCSXe69ubgUChEOSx4G5d+bf4ovZR4Bnla+95ocrgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}