SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389efcaf59bd2e66b15a7ac334967010280c60bd7534cdd78d96da8c35eaaecd' 
  AND token = 'IxED+g1FslB8vGiNeDovGYszr5459ZiH/RtgM6vcOQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}