SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cf84b6d61378194709f7ca068d9f62d4cfcd1ea3cce036b9b61f71308afbf6a' 
  AND token = 'S2vi1dUg8C6UT49CpKypK+ilwa74/cTDYPzRBFOdIaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}