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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc526e9002d90f162cf51d1ac704ef4a7bf10858a91d1818bceee19d76ced93f' 
  AND token = 'w+EgB4JJZS3MpkyX/oJH3wiuF6EqpYLmoDwCZ1xy7Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}