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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '431e6b97e0b2732a52c2b2293e488e2cdc5a117da9a0b2c6c035ba1f612c0cfe' 
  AND token = 'nKFl3S/rH+2op0mLSdsIb0rFJdlEPFH/RDiL4hwCm9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}