SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '204607c43b635eed51925099a574695c5a64bb3a9bcdfcf5d5aa76df95bc5e34' 
  AND token = 'PumH3XL3P1rouwIOznwdLB1k4ktKIZygb0XWh5LxfI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}