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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a361769f8a789538fd604636ab16e70df6714dd0ed15c60442bb27be1f55f16' 
  AND token = 'UpYkm4yIr5FeuAiW3xtH2FCt5pkYdxNcoZeL+EtHo24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}