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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbaab86e4200f598b60023722c36e288e9c89ff01bd92bd3d83f23127285d0f9' 
  AND token = 'r/VIRL/vXfjIjTYqvXB54RigsZq5imOlnBlbM1Ti2pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}