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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '337f17202d459f3650b90d927bb3d5cfc999494a7027d0e0c3796b1f3432a6dd' 
  AND token = 'Y4cDzzleZvZhYkPMEDAXaR2R5GnnCR+tGkxyF703D2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}