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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '432778941657f0cd2dd6b668c2f190276d42339e47f60bdb7141bd0f9ff9cfd3' 
  AND token = '2javK0EzXrH2eStTPFBID/b4uwL+1AlFj4FZL0XRMDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}