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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35b12d6a0aba597e69621d62823d8f06db82d5e452c972c2f9df8bcd71231390' 
  AND token = '0ESgfbiNiF/Yv2Nq9T9Qr0yWYGA8WE7aG9l63kd6thM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}