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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '483ba2bf875eb5f559b217b993cccf62feab67f468e6fed56ae45e9dbc8a22d4' 
  AND token = 'LlyVs2GLDqkfLmmqzsVc8sjg8CiwOI0LW54ihy/btW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}