SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd75b37d20b6e4657f632907d9257c890322196c8d80915b972ae7bcfe216c33a' 
  AND token = 'VJqmjSE7gbktJ6xRX1K/i+6IH3E0c0IY7C0DpFS3D94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}