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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ace4b4f1dfb33d8d4e3d3a38798afd2fb0327acd647a300f23822705900ab730' 
  AND token = 'WUxCSwsDItinrhP23mkDbdDxEaIzFlYmMDk1ehmSWRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}