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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af49fdf32473b024914ca148934f8d31ed7baac0927350f48c88237db0fdaf69' 
  AND token = '9TJdyGCqnwFytv5RX8oM82ak5QoO06HmrHbbGuGwdMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}