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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66e71927ce27b3399fdebc985f76900aa1e6f31b36ba2b9cdbda6309d589877' 
  AND token = 'qN2vfXt/TMXzKMyRigCAJyx+9m3FpVy8UXpMb9Qr6u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}