SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5278c7c346462d48dc41dec5d2f23e3b65434da32421e7ed76694785cf97497d' 
  AND token = 'OmviskLfLqgZ2QNtqV69FVmuIIWqZ7MNj/aGIT1Pe7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}