SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e79b2503a03d2e90877bcdfe44a75066cb85cccf56503f569677d6678755f03' 
  AND token = 'j0nYJGqmQ6t0aCuJums4YMsz/v3o5xRXJ2A0RZ6ncLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}