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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d728c8f64f4ec4943d25523821d1ba5706a155740a57af9ac4af27f36b9744f' 
  AND token = '402OHbRIqpcoHYihro9bk7zDnDA2IOXcQiyKopiuHEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}