SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03a00b71543d96ed261e6b1ee53dff8ddd963e7ddd427de05fc9e3655fa09cce' 
  AND token = 'o+KualFSTWfdbmTS3hP9Y+B7ASmNP1WHePD4jVuLou8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}