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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9b3aee0389203260e36e7ee83fec9e8f0132afb51ec7bc8376fbed5db7c64b7' 
  AND token = 'hMMes8NzZLaZyhE7OTEczOJV2d8SwrYRXZ+gbq3lq/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}