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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1cea278c36d584ddce869d3bfc2b20ea441ef28b3c7df6f678e3075a752b736' 
  AND token = 'bfFcZdLHLwoXVsWVKz+j0L90jasg9znhRD5LLRZFTn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}