SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2326080754cd5d82c428ed210ea182c0feea98cef12d3a18fe8f18251888fb87' 
  AND token = 'Gt7tHaEYG3u15OwPiMsfq+npxoygs4HAeOchtRL8aGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}