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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '722812fe01e77c95a2eaeb53e71b49ba0ab3e6672cc5c20b777511352b1df8b1' 
  AND token = '9Xf/J5bHclVWK4+W0d3676WAD1lAt/6q0yi431IsWxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}