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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91d9843262d1ab1d86f2b2ece01dad823a422b688f3a82453e31549f9bfbc0b5' 
  AND token = 'jwF/wcBT8x2OSn2/f/8DfKU86jM6HWeno/uQN5s9Ezs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}