SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adef7c69d8837c3a782329fb6315a3e75c11bf048067dfa8460a071d146deac4' 
  AND token = 'v4baX548cnbAK9BHmRXHHE80OrY5FkBay21aU/TqRVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}