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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13c3ced41dd07c2265da6fc4694b2a9273406d6a0ffce5321a421ee800f7998f' 
  AND token = 'uk3cpMQGG7g4T6rhScu0/lV7HjPb5wZDA8xSBOpEIaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}