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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '627fe9a49053933423a97bcabc1c171d011f136cb159124820e119ab059e9703' 
  AND token = 'Ut0t3akD8amZG/ph1wTIzRVkFlLCt7zfuEJFNiXbcpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}