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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad145de0856f1e8c6066a5432a9f5d1aab8e540a9b7e01e8f1abd59866d9000' 
  AND token = 'L+oHC33gJHoJlNBz6yIZ01PCz+PATgcZ1sq3PhtSdzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00085

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}