SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5382acfd5e49f3bc5648059a11ea18dd5148d89167afe9a4b52a8398f0d973f3' 
  AND token = 'ieU0a+h8kRWSPYDVtCSZ/APXKtHv1jwXMCgutyxVINA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}