SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46baa1d60d5c2ff722e588741d707ab91bc1b00fb485c6bf0db039f911f33208' 
  AND token = '0aFAHThI5r8UJ+JoPuQtMN3wN0QwZk61+b1fxkj6avQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}