SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee5fef56cecd48fbef4245c09117c6f0a51798f6971bd036102fd6b684b6364f' 
  AND token = '8xdJXfQE5ziunkI+ObjLjjmlIKyRSa/gi82rxQbC21Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}