SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b287f5afea4db9dd477bcef5e091cf9acb1b4b89166e6f30d0645448f4858036' 
  AND token = 'c0ZDkXPDYrdltyc9zz1HRNsN2pL0wY/UflihIfZ3F3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}