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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '141e80b031ea53b0fdb104776af949aef77f1a5ec727c62cfbb44d5a1588f99c' 
  AND token = 'sy6Xwc7NmTh+AtdvM564DrKtI4JkbNFicNf58Iv0CD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}