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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1493dc5a0ad5dcacc9278d5c0bd0048d0b91b5af0dfd7b62e4871d355c3409db' 
  AND token = 'XxweqsgL9sIw+zuuYenqkwBkQ+bmOoRmhpEaK4LrK5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}