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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ae8025cc736c9a3d71039a6cace30f2530a001f5ae5a7e7615f065631e50870' 
  AND token = 'bMPC2k9DeV++wuMVcpsfIjOg8Q0jxiQMvx3w0QOYjuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}