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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5166e3ce20b23e6c6a9d23988e4a02a77a3020ab612bceb8c27da3cca6778c' 
  AND token = 'W/LxFKNW4/DZ8tjU7samduhiI2LDvEZWL2ZFBxmn1gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}