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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a8bb3db64dc3e177e090a12d6ee6d6353ff39cf0b23b3d1e0fa70c42cfb513b' 
  AND token = 'Cw4w2Hekwvz+cDMkkkHK5t+HdvGVYtuCgj2nu8nXS08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}