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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d115c5f7a8b0e22fda9b7276e90c8e519b62b44bafd9b194b76e06679ec396' 
  AND token = 'R/nbk0A6iyUeJODtQ4uXcE2xCVzqpYr5vgS9cuxs5MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}