SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbce01524e73a5405e7bad452a0fe564e38f9df8efe721c04f6456950f3c1d1e' 
  AND token = 'jDsnm5NOTPLvRJoAxMKjb7ypkIVtQdkyP+/ZUMbC/9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}